A compendium of next-generation patient-derived models for diverse cancers

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10806-y

The international collaboration of the Human Cancer Models Initiative presents a comprehensive resource of next-generation cancer models from 2,780 donors with 25 cancer types and integrated tumour–model genomic, transcriptomic and epigenomic analyses.