Antigen presentation by CD40<sup>+</sup>MHC-II<sup>+</sup> astrocytes promotes CNS autoimmunity
Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10860-6
Astrocytes promote central nervous system (CNS) immunity through antigen presentation and activation of CD40 in astrocytes by CD40L expressed by CD4+ T cells in a model of experimental autoimmune encephalomyelitis.